Apparati is developing innovative solutions to create more sustainable processes in nucleotide synthesis using biologically-derived, animal-free starting material and enzyme catalysis.

A major bottle-neck in the production of COVID-19 mRNA vaccines was the chemical synthesis of lipids to make lipid nanoparticles. Apparati is committed to developing sustainable methods to produce lipids suitabe for LNP production.

Fermentation may be an unsuitable route to produce unstable or toxic proteins. In addition, large-scale fermentation can be energy-intensive and capital-intensive. CFPS is a possible solution to issues with fermentation if it were not so cost-prohibitive. Apparati is solving the techno-economic issues with CFPS by developing innovative synthetic biology methods to reduce the cost of critical components.